InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: UMPS

Summary

InnateDB Protein

IDBP-685212.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UMPS

Protein Name

uridine 5'-monophosphate synthase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018248

InnateDB Gene

IDBG-633496 (UMPS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004588	orotate phosphoribosyltransferase activity
GO:0004590	orotidine-5'-phosphate decarboxylase activity
GO:0016740	transferase activity
GO:0016757	transferase activity, transferring glycosyl groups
GO:0016829	lyase activity
GO:0016831	carboxy-lyase activity

Biological Process

GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221	pyrimidine nucleotide biosynthetic process
GO:0006222	UMP biosynthetic process
GO:0008152	metabolic process
GO:0009116	nucleoside metabolic process
GO:0044205	'de novo' UMP biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000836 Phosphoribosyltransferase domain
IPR001754 Orotidine 5\'-phosphate decarboxylase domain
IPR004467 Orotate phosphoribosyl transferase domain
IPR011060 Ribulose-phosphate binding barrel
IPR014732 Orotidine 5\'-phosphate decarboxylase
IPR029057 Phosphoribosyltransferase-like

PFAM

PF00156
PF00215

PRINTS

PIRSF

SMART

SM00934

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P31754