InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HIBADH

Summary

InnateDB Protein

IDBP-685268.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HIBADH

Protein Name

3-hydroxyisobutyrate dehydrogenase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001374

InnateDB Gene

IDBG-633547 (HIBADH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
GO:0008442	3-hydroxyisobutyrate dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662	coenzyme binding
GO:0051287	NAD binding

Biological Process

GO:0006098	pentose-phosphate shunt
GO:0006574	valine catabolic process
GO:0009083	branched-chain amino acid catabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR011548 3-hydroxyisobutyrate dehydrogenase
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF03446
PF02826
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2HJD7

PhosphoSite