Version 5.4
| Bos taurus Protein: CPSF2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-685417.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CPSF2 | ||||||||
| Protein Name | Cleavage and polyadenylation specificity factor subunit 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000013500 | ||||||||
| InnateDB Gene | IDBG-633683 (CPSF2) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001279
Beta-lactamase-like IPR011108 RNA-metabolising metallo-beta-lactamase IPR022712 Beta-Casp domain |
||||||||
| PFAM |
PF00753
PF07521 PF10996 |
||||||||
| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00849
SM01027 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q10568 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 327689 | ||||||||
| UniGene | Bt.4077 | ||||||||
| RefSeq | NP_787002 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | X75931 | ||||||||
| GenPept | CAA53535 | ||||||||