Version 5.4
Bos taurus Protein: TFRC
Summary
InnateDB Protein IDBP-685631.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFRC
Protein Name transferrin receptor (p90, CD71)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000043726
InnateDB Gene IDBG-633841 (TFRC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003725 double-stranded RNA binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0042802 identical protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006508 proteolysis
GO:0006879 cellular iron ion homeostasis
GO:0030316 osteoclast differentiation
GO:0045780 positive regulation of bone resorption
GO:0097286 iron ion import
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID
InterPro IPR003137 Protease-associated domain, PA
IPR007365 Transferrin receptor-like, dimerisation domain
IPR007484 Peptidase M28
PFAM PF02225
PF04253
PF04389
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BIG6
UniProt Splice Variant
Entrez Gene 504698
UniGene
RefSeq NP_001193506
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001685 DAAA02001686
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca