Bos taurus Protein: FRS2
Summary
InnateDB Protein IDBP-685645.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRS2
Protein Name fibroblast growth factor receptor substrate 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025495
InnateDB Gene IDBG-633904 (FRS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005104 fibroblast growth factor receptor binding
GO:0005158 insulin receptor binding
GO:0005168 neurotrophin TRKA receptor binding
GO:0005515 protein binding
Biological Process
GO:0000187 activation of MAPK activity
GO:0001702 gastrulation with mouth forming second
GO:0001759 organ induction
GO:0002088 lens development in camera-type eye
GO:0003281 ventricular septum development
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007405 neuroblast proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0008595 anterior/posterior axis specification, embryo
GO:0030900 forebrain development
GO:0042981 regulation of apoptotic process
GO:0046619 optic placode formation involved in camera-type eye formation
GO:0050678 regulation of epithelial cell proliferation
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0070307 lens fiber cell development
GO:0070372 regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
Protein Structure and Domains
PDB ID
InterPro IPR002404 Insulin receptor substrate-1, PTB
PFAM PF02174
PRINTS PR00628
PIRSF
SMART SM00310
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1B7I9
UniProt Splice Variant
Entrez Gene 538624
UniGene Bt.61417
RefSeq XP_002687431
HUGO HGNC:16971
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013228
GenPept