Bos taurus Protein: IGFBP1 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-685752.2 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | IGFBP1 | ||||||
Protein Name | Insulin-like growth factor-binding protein 1 | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Protein | ENSBTAP00000055280 | ||||||
InnateDB Gene | IDBG-634003 (IGFBP1) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity). {ECO:0000250}. | ||||||
Subcellular Localization | Secreted. | ||||||
Disease Associations | |||||||
Tissue Specificity | |||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | |||||||
InterPro |
IPR000716
Thyroglobulin type-1 IPR000867 Insulin-like growth factor-binding protein, IGFBP IPR009030 Insulin-like growth factor binding protein, N-terminal IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata IPR022322 Insulin-like growth factor-binding protein 1 |
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PFAM |
PF00086
PF00219 |
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PRINTS |
PR01976
PR01977 |
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PIRSF | |||||||
SMART |
SM00211
SM00121 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | P24591 | ||||||
PhosphoSite | PhosphoSite- | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 282259 | ||||||
UniGene | Bt.190 | ||||||
RefSeq | NP_776979 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | BC111197 X54979 | ||||||
GenPept | AAI11198 CAA38723 | ||||||