Version 5.4
Bos taurus Protein: LCAT
Summary
InnateDB Protein IDBP-685788.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LCAT
Protein Name phosphatidylcholine-sterol acyltransferase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024018
InnateDB Gene IDBG-634038 (LCAT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity
GO:0005515 protein binding
GO:0008374 O-acyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
GO:0034186 apolipoprotein A-I binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006644 phospholipid metabolic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0008203 cholesterol metabolic process
GO:0030301 cholesterol transport
GO:0034372 very-low-density lipoprotein particle remodeling
GO:0034375 high-density lipoprotein particle remodeling
GO:0034435 cholesterol esterification
GO:0042158 lipoprotein biosynthetic process
GO:0042632 cholesterol homeostasis
GO:0043691 reverse cholesterol transport
GO:0090107 regulation of high-density lipoprotein particle assembly
Cellular Component
GO:0005615 extracellular space
GO:0034364 high-density lipoprotein particle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF02450
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2KIW4
UniProt Splice Variant
Entrez Gene 510960
UniGene Bt.106731
RefSeq NP_001039534
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112484 DAAA02046690
GenPept AAI12485

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca