Version 5.4
| Bos taurus Protein: TBC1D2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-685812.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | TBC1D2 | ||||||||
| Protein Name | TBC1 domain family member 2A | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000026052 | ||||||||
| InnateDB Gene | IDBG-634058 (TBC1D2) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | May act as a GTPase-activating protein for Rab family protein(s). Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and further inhibition of cadherin degradation (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000195
Rab-GTPase-TBC domain IPR001849 Pleckstrin homology domain |
||||||||
| PFAM |
PF00566
PF00169 |
||||||||
| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00164
SM00233 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A6QP29 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 513828 | ||||||||
| UniGene | Bt.20886 | ||||||||
| RefSeq | NP_001095451 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC149120 | ||||||||
| GenPept | AAI49121 | ||||||||