Version 5.4
Bos taurus Protein: MCF2L
Summary
InnateDB Protein IDBP-686078.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCF2L
Protein Name MCF.2 cell line derived transforming sequence-like
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000035199
InnateDB Gene IDBG-634207 (MCF2L)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005545 1-phosphatidylinositol binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005615 extracellular space
GO:0016020 membrane
GO:0030027 lamellipodium
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR001251 CRAL-TRIO domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR002017 Spectrin repeat
IPR018159 Spectrin/alpha-actinin
PFAM PF00621
PF00650
PF13716
PF00018
PF14604
PF00169
PF00435
PRINTS PR00452
PIRSF
SMART SM00325
SM00516
SM00326
SM00233
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BK14
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:14576
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02034946
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca