InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARRB2

Summary

InnateDB Protein

IDBP-686154.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARRB2

Protein Name

arrestin, beta 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000046840

InnateDB Gene

IDBG-634360 (ARRB2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 271 interaction(s) predicted by orthology.

Predicted by orthology
Total	271 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0031625	ubiquitin protein ligase binding
GO:0031701	angiotensin receptor binding
GO:0032947	protein complex scaffold
GO:0043422	protein kinase B binding

Biological Process

GO:0001932	regulation of protein phosphorylation
GO:0002031	G-protein coupled receptor internalization
GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002092	positive regulation of receptor internalization
GO:0006366	transcription from RNA polymerase II promoter
GO:0007165	signal transduction
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007628	adult walking behavior
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0016567	protein ubiquitination
GO:0031397	negative regulation of protein ubiquitination
GO:0031398	positive regulation of protein ubiquitination
GO:0031623	receptor internalization
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032226	positive regulation of synaptic transmission, dopaminergic
GO:0032691	negative regulation of interleukin-1 beta production
GO:0032695	negative regulation of interleukin-12 production
GO:0032715	negative regulation of interleukin-6 production
GO:0032720	negative regulation of tumor necrosis factor production
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
GO:0060326	cell chemotaxis
GO:0060765	regulation of androgen receptor signaling pathway
GO:0070374	positive regulation of ERK1 and ERK2 cascade