InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DLG4

Summary

InnateDB Protein

IDBP-686352.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DLG4

Protein Name

discs, large homolog 4 (Drosophila)

Synonyms

LLGL1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003326

InnateDB Gene

IDBG-634574 (DLG4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 346 interaction(s) predicted by orthology.

Predicted by orthology
Total	346 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0097110	scaffold protein binding

Biological Process

GO:0006461	protein complex assembly
GO:0016188	synaptic vesicle maturation
GO:0035176	social behavior
GO:0035418	protein localization to synapse
GO:0035641	locomotory exploration behavior
GO:0045184	establishment of protein localization
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0050885	neuromuscular process controlling balance
GO:0071625	vocalization behavior
GO:2000821	regulation of grooming behavior

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0008021	synaptic vesicle
GO:0008328	ionotropic glutamate receptor complex
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0030054	cell junction
GO:0030425	dendrite
GO:0030863	cortical cytoskeleton
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
GO:0032281	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0043197	dendritic spine
GO:0044224	juxtaparanode region of axon
GO:0044300	cerebellar mossy fiber
GO:0044306	neuron projection terminus
GO:0044309	neuron spine
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0060076	excitatory synapse
GO:0097481	neuronal postsynaptic density

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR016313 Disks large 1
IPR019583 PDZ-associated domain of NMDA receptors
IPR019590 Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM