InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NFAT5

Summary

InnateDB Protein

IDBP-686362.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NFAT5

Protein Name

nuclear factor of activated T-cells 5, tonicity-responsive

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017847

InnateDB Gene

IDBG-634541 (NFAT5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0001816	cytokine production
GO:0006355	regulation of transcription, DNA-templated
GO:0010628	positive regulation of gene expression
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0070884	regulation of calcineurin-NFAT signaling cascade

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR002909 IPT domain
IPR008366 Nuclear factor of activated T cells (NFAT)
IPR008967 p53-like transcription factor, DNA-binding
IPR011539 Rel homology domain
IPR014756 Immunoglobulin E-set

PFAM

PF01833
PF00554

PRINTS

PR01789

PIRSF

SMART

SM00429

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt