InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BCL6

Summary

InnateDB Protein

IDBP-686389.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BCL6

Protein Name

B-cell CLL/lymphoma 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001978

InnateDB Gene

IDBG-634562 (BCL6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 124 interaction(s) predicted by orthology.

Predicted by orthology
Total	124 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0031490	chromatin DNA binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000060	protein import into nucleus, translocation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000902	cell morphogenesis
GO:0001953	negative regulation of cell-matrix adhesion
GO:0002467	germinal center formation
GO:0002829	negative regulation of type 2 immune response
GO:0006974	cellular response to DNA damage stimulus
GO:0007266	Rho protein signal transduction
GO:0007283	spermatogenesis
GO:0008104	protein localization
GO:0008285	negative regulation of cell proliferation
GO:0030036	actin cytoskeleton organization
GO:0030183	B cell differentiation
GO:0030308	negative regulation of cell growth
GO:0030890	positive regulation of B cell proliferation
GO:0032319	regulation of Rho GTPase activity
GO:0032764	negative regulation of mast cell cytokine production
GO:0035024	negative regulation of Rho protein signal transduction
GO:0042092	type 2 immune response
GO:0042127	regulation of cell proliferation
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0043380	regulation of memory T cell differentiation
GO:0045596	negative regulation of cell differentiation
GO:0045629	negative regulation of T-helper 2 cell differentiation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0048294	negative regulation of isotype switching to IgE isotypes
GO:0048821	erythrocyte development
GO:0050727	regulation of inflammatory response
GO:0051272	positive regulation of cellular component movement