InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: USP15

Summary

InnateDB Protein

IDBP-686554.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP15

Protein Name

ubiquitin carboxyl-terminal hydrolase 15

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000037402

InnateDB Gene

IDBG-634754 (USP15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 87 interaction(s) predicted by orthology.

Predicted by orthology
Total	87 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004197	cysteine-type endopeptidase activity
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0005160	transforming growth factor beta receptor binding
GO:0008233	peptidase activity
GO:0008234	cysteine-type peptidase activity
GO:0016787	hydrolase activity
GO:0036459	ubiquitinyl hydrolase activity
GO:0042802	identical protein binding
GO:0046332	SMAD binding

Biological Process

GO:0006508	proteolysis
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0016579	protein deubiquitination
GO:0030509	BMP signaling pathway
GO:0035520	monoubiquitinated protein deubiquitination
GO:0060389	pathway-restricted SMAD protein phosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
IPR013792 RNA 3\'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
IPR029071 Ubiquitin-related domain

PFAM

PF00443
PF06337

PRINTS

PIRSF

SMART

SM00695

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2HJE4