Bos taurus Protein: SPSB3
Summary
InnateDB Protein IDBP-686616.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPSB3
Protein Name SPRY domain-containing SOCS box protein 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022024
InnateDB Gene IDBG-634824 (SPSB3)
Protein Structure
UniProt Annotation
Function May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001496 SOCS protein, C-terminal
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF07525
PF00622
PRINTS
PIRSF
SMART SM00253
SM00969
SM00449
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHZ2
PhosphoSite PhosphoSite-
TrEMBL M5FHR0
UniProt Splice Variant
Entrez Gene 515661
UniGene Bt.21275
RefSeq NP_001029678
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104512 GJ062847
GenPept AAI04513 DAA15586