Version 5.4
| Bos taurus Protein: PDLIM2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-686656.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | PDLIM2 | ||||||||||
| Protein Name | PDZ and LIM domain protein 2 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000009697 | ||||||||||
| InnateDB Gene | IDBG-634857 (PDLIM2) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes at the cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN) (By similarity). {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR001478
PDZ domain IPR001781 Zinc finger, LIM-type |
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| PFAM |
PF00595
PF13180 PF00412 |
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART |
SM00228
SM00132 |
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q3T0C8 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 512907 | ||||||||||
| UniGene | Bt.7871 | ||||||||||
| RefSeq | NP_001029602 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC102452 | ||||||||||
| GenPept | AAI02453 | ||||||||||