InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TSFM

Summary

InnateDB Protein

IDBP-686664.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TSFM

Protein Name

Elongation factor Ts, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022496

InnateDB Gene

IDBG-634869 (TSFM)

Protein Structure

UniProt Annotation

Function

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. {ECO:0000255HAMAP-Rule:MF_03135}.

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003746	translation elongation factor activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006412	translation
GO:0006414	translational elongation

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR009060 UBA-like
IPR014039 Translation elongation factor EFTs/EF1B, dimerisation

PFAM

PF00627
PF00889

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P43896

PhosphoSite