Version 5.4
Bos taurus Protein: POP4
Summary
InnateDB Protein IDBP-686728.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POP4
Protein Name Ribonuclease P protein subunit p29
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002876
InnateDB Gene IDBG-634936 (POP4)
Protein Structure
UniProt Annotation
Function Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0004540 ribonuclease activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0006364 rRNA processing
GO:0006379 mRNA cleavage
GO:0008033 tRNA processing
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:0005730 nucleolus
GO:0030677 ribonuclease P complex
Protein Structure and Domains
PDB ID
InterPro IPR002730 Ribonuclease P/MRP, subunit p29
IPR016848 Ribonuclease P/MRP, p29 subunit
IPR023534 Rof/RNase P-like
PFAM PF01868
PRINTS
PIRSF PIRSF027081
SMART SM00538
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KIB9
PhosphoSite PhosphoSite-
TrEMBL Q58DW8
UniProt Splice Variant
Entrez Gene 614870
UniGene Bt.21490
RefSeq NP_001106753
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112695 BT021479 DAAA02046773
GenPept AAI12696 AAX46326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca