InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ANAPC15

Summary

InnateDB Protein

IDBP-686836.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANAPC15

Protein Name

Protein HSPC020 homolog

Synonyms

APC15; C15H11orf51;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003902

InnateDB Gene

IDBG-635036 (ANAPC15)

Protein Structure

UniProt Annotation

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20 (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0007049	cell cycle
GO:0007067	mitotic nuclear division
GO:0051301	cell division
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint

Cellular Component

GO:0005680

anaphase-promoting complex

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3SZ31

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

505356

UniGene

RefSeq

NP_001029415

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103197

GenPept

AAI03198