InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DDX20

Summary

InnateDB Protein

IDBP-686838.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX20

Protein Name

probable ATP-dependent RNA helicase DDX20

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024914

InnateDB Gene

IDBG-635035 (DDX20)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.

Predicted by orthology
Total	45 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000387	spliceosomal snRNP assembly
GO:0006200	ATP catabolic process
GO:0008152	metabolic process
GO:0043065	positive regulation of apoptotic process
GO:0048477	oogenesis
GO:0050810	regulation of steroid biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0017053	transcriptional repressor complex
GO:0032797	SMN complex
GO:0034719	SMN-Sm protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite