Version 5.4
Bos taurus Protein: AHCYL1
Summary
InnateDB Protein IDBP-687069.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AHCYL1
Protein Name S-adenosylhomocysteine hydrolase-like 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025149
InnateDB Gene IDBG-635246 (AHCYL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 79 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 79 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004013 adenosylhomocysteinase activity
GO:0004455 ketol-acid reductoisomerase activity
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0051287 NAD binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0008652 cellular amino acid biosynthetic process
GO:0009396 folic acid-containing compound biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000043 Adenosylhomocysteinase
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
IPR013116 Acetohydroxy acid isomeroreductase, catalytic
IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain
IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
PFAM PF05221
PF02826
PF07991
PF00670
PF02882
PRINTS
PIRSF PIRSF001109
SMART SM00996
SM00997
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QNP1
UniProt Splice Variant
Entrez Gene 505511
UniGene Bt.37868
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC148933 DAAA02007557 DAAA02007558 DAAA02007559
GenPept AAI48934

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca