Version 5.4
Bos taurus Protein: GTF2H5
Summary
InnateDB Protein IDBP-687098.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2H5
Protein Name ral transcription factor IIH subunit 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000011263
InnateDB Gene IDBG-635273 (GTF2H5)
Protein Structure
UniProt Annotation
Function Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000182 rDNA binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006362 transcription elongation from RNA polymerase I promoter
GO:0006364 rRNA processing
GO:0006974 cellular response to DNA damage stimulus
GO:0071480 cellular response to gamma radiation
Cellular Component
GO:0000439 core TFIIH complex
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR009400 TFIIH subunit TTDA/Tfb5
PFAM PF06331
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2T9Z5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 518046
UniGene Bt.21230
RefSeq NP_001035627
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111195
GenPept AAI11196

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca