Version 5.4
Bos taurus Protein: PGP
Summary
InnateDB Protein IDBP-687143.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGP
Protein Name Phosphoglycolate phosphatase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013127
InnateDB Gene IDBG-635315 (PGP)
Protein Structure
UniProt Annotation
Function Phosphatase with broad substrate specificity. Has high phosphatase activity toward ADP, ATP, GDP, GTP and p- nitrophenylphosphate. Has tyrosine-protein phosphatase activity (in vitro). Has very low activity with pyridoxal 5'-phosphate (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0008967 phosphoglycolate phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008152 metabolic process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006349 2-phosphoglycolate phosphatase, eukaryotic
IPR006357 HAD-superfamily hydrolase, subfamily IIA
IPR023214 HAD-like domain
PFAM PF13344
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2T9S4
PhosphoSite PhosphoSite-
TrEMBL M5FJY9
UniProt Splice Variant
Entrez Gene 538173
UniGene Bt.32423
RefSeq NP_001033261
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111291 GJ062847
GenPept AAI11292 DAA15609

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca