Version 5.4
| Bos taurus Protein: ZFYVE21 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-687322.2 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | ZFYVE21 | ||||||||||
| Protein Name | Zinc finger FYVE domain-containing protein 21 | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Protein | ENSBTAP00000041951 | ||||||||||
| InnateDB Gene | IDBG-635479 (ZFYVE21) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Cell junction, focal adhesion. Cytoplasmic vesicle {ECO:0000250}. Endosome {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | |||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | |||||||||||
| InterPro |
IPR000306
FYVE zinc finger IPR011011 Zinc finger, FYVE/PHD-type IPR017455 Zinc finger, FYVE-related |
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| PFAM |
PF01363
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART |
SM00064
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q05B78 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | F1MHW4 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 511413 | ||||||||||
| UniGene | Bt.21805 | ||||||||||
| RefSeq | NP_001073055 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BC122654 DAAA02053315 | ||||||||||
| GenPept | AAI22655 | ||||||||||