Version 5.4
Bos taurus Protein: CEP41
Summary
InnateDB Protein IDBP-687348.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP41
Protein Name centrosomal protein 41kDa
Synonyms TSGA14;
Species Bos taurus
Ensembl Protein ENSBTAP00000009747
InnateDB Gene IDBG-635507 (CEP41)
Protein Structure
UniProt Annotation
Function Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes mainly to the cilium basal body and in primary cilia. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0018095 protein polyglutamylation
GO:0030030 cell projection organization
GO:0042384 cilium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0016020 membrane
GO:0036064 ciliary basal body
GO:0042995 cell projection
GO:0072372 primary cilium
Protein Structure and Domains
PDB ID
InterPro IPR001763 Rhodanese-like domain
PFAM PF00581
PRINTS
PIRSF
SMART SM00450
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt F1MUG2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 506914
UniGene Bt.34524
RefSeq NP_001179050
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02011518 DAAA02011519
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca