InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AMDHD2

Summary

InnateDB Protein

IDBP-687372.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AMDHD2

Protein Name

Putative N-acetylglucosamine-6-phosphate deacetylase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001355

InnateDB Gene

IDBG-635532 (AMDHD2)

Protein Structure

UniProt Annotation

Function

Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity
GO:0016787	hydrolase activity
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872	metal ion binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006044	N-acetylglucosamine metabolic process
GO:0019262	N-acetylneuraminate catabolic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR003764 N-acetylglucosamine-6-phosphate deacetylase
IPR006680 Amidohydrolase 1
IPR011059 Metal-dependent hydrolase, composite domain
IPR013108 Amidohydrolase 3

PFAM

PF01979
PF07969

PRINTS

PIRSF

PIRSF038994

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A7MBC0