Version 5.4
Bos taurus Protein: FXYD1
Summary
InnateDB Protein IDBP-687394.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FXYD1
Protein Name Phospholemman
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000042049
InnateDB Gene IDBG-635550 (FXYD1)
Protein Structure
UniProt Annotation
Function May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005254 chloride channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0034707 chloride channel complex
Protein Structure and Domains
PDB ID
InterPro IPR000272 Ion-transport regulator, FXYD motif
PFAM PF02038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SZX0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 616139
UniGene
RefSeq NP_001069878
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102671
GenPept AAI02672

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca