Version 5.4
Bos taurus Protein: GAPDHS
Summary
InnateDB Protein IDBP-687554.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAPDHS
Protein Name Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021166
InnateDB Gene IDBG-635698 (GAPDHS)
Protein Structure
UniProt Annotation
Function May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0030317 sperm motility
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005929 cilium
GO:0031514 motile cilium
GO:0035686 sperm fibrous sheath
GO:0097228 sperm principal piece
Protein Structure and Domains
PDB ID
InterPro IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family
PFAM PF00044
PF02800
PRINTS PR00078
PIRSF PIRSF000149
SMART SM00846
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KJE5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 532231
UniGene Bt.91447
RefSeq NP_001035642
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105381
GenPept AAI05382

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca