InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ETV5

Summary

InnateDB Protein

IDBP-68761.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ETV5

Protein Name

ets variant 5

Synonyms

ERM;

Species

Homo sapiens

Ensembl Protein

ENSP00000306894

InnateDB Gene

IDBG-408468 (ETV5)

Protein Structure

UniProt Annotation

Function

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0016563	transcription activator activity
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007274	neuromuscular synaptic transmission
GO:0007626	locomotory behavior
GO:0009887	organ morphogenesis
GO:0030154	cell differentiation
GO:0034599	cellular response to oxidative stress
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045941	positive regulation of transcription
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048133	male germ-line stem cell division
GO:0050807	regulation of synapse organization
GO:0060252	positive regulation of glial cell proliferation
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
GO:0071340	skeletal muscle acetylcholine-gated channel clustering