Version 5.4
Bos taurus Protein: TAC3
Summary
InnateDB Protein IDBP-687724.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAC3
Protein Name Tachykinin-3Neurokinin-B
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029067
InnateDB Gene IDBG-635852 (TAC3)
Protein Structure
UniProt Annotation
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007217 tachykinin receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003635 Neurokinin-B/Tachykinin-3
PFAM PF03823
PRINTS PR01828
PIRSF PIRSF001843
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08858
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281513
UniGene Bt.37192
RefSeq NP_851360
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL M14347 M14348 M14349 M14350 M14351
GenPept AAA30723

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca