Version 5.4
Bos taurus Protein: NUDT2
Summary
InnateDB Protein IDBP-687747.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT2
Protein Name Bis(5'-nucleosyl)-tetraphosphatase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000042493
InnateDB Gene IDBG-635877 (NUDT2)
Protein Structure
UniProt Annotation
Function Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
GO:0005525 GTP binding
GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000086 NUDIX hydrolase domain
IPR003565 Bis(5\'-nucleosyl)-tetraphosphatase
IPR015797 NUDIX hydrolase domain-like
IPR020476 NUDIX hydrolase
PFAM PF00293
PRINTS PR01405
PR00502
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q29RJ1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 768044
UniGene Bt.2818
RefSeq NP_001070570
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114149
GenPept AAI14150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca