Version 5.4
Bos taurus Protein: CTRC
Summary
InnateDB Protein IDBP-687758.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTRC
Protein Name Chymotrypsin-C
Synonyms bPTLP;
Species Bos taurus
Ensembl Protein ENSBTAP00000033942
InnateDB Gene IDBG-635884 (CTRC)
Protein Structure
UniProt Annotation
Function Has chymotrypsin-type protease activity and hypocalcemic activity. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space {ECO:0000250}.
Disease Associations
Tissue Specificity Pancreas. {ECO:0000269PubMed:7556081, ECO:0000269PubMed:9223647}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7M3E1
PhosphoSite PhosphoSite-
TrEMBL B0JYP7
UniProt Splice Variant
Entrez Gene 514047
UniGene Bt.45270
RefSeq NP_001092435
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134798 BC142035 BC151506 CK771392
GenPept AAI34799 AAI42036 AAI51507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca