Version 5.4
| Bos taurus Protein: EFHD2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-687759.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EFHD2 | ||||||||
| Protein Name | EF-hand domain-containing protein D2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000042244 | ||||||||
| InnateDB Gene | IDBG-635891 (EFHD2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane raft {ECO:0000250}. Note=In a mouse immature B-cell line WEHI-231. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002048
EF-hand domain |
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| PFAM |
PF00036
PF13202 PF13405 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00054
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A5D7A0 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514259 | ||||||||
| UniGene | Bt.73778 | ||||||||
| RefSeq | NP_001096715 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC140480 | ||||||||
| GenPept | AAI40481 | ||||||||