Bos taurus Protein: EFHD2 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-687759.2 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | EFHD2 | ||||||||
Protein Name | EF-hand domain-containing protein D2 | ||||||||
Synonyms | |||||||||
Species | Bos taurus | ||||||||
Ensembl Protein | ENSBTAP00000042244 | ||||||||
InnateDB Gene | IDBG-635891 (EFHD2) | ||||||||
Protein Structure |
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UniProt Annotation | |||||||||
Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. {ECO:0000250}. | ||||||||
Subcellular Localization | Membrane raft {ECO:0000250}. Note=In a mouse immature B-cell line WEHI-231. {ECO:0000250}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | |||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | |||||||||
InterPro |
IPR002048
EF-hand domain |
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PFAM |
PF00036
PF13202 PF13405 |
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PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00054
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | A5D7A0 | ||||||||
PhosphoSite | PhosphoSite- | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 514259 | ||||||||
UniGene | Bt.73778 | ||||||||
RefSeq | NP_001096715 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | BC140480 | ||||||||
GenPept | AAI40481 | ||||||||