InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NPHS1

Summary

InnateDB Protein

IDBP-687891.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPHS1

Protein Name

nephrosis 1, congenital, Finnish type (nephrin)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010289

InnateDB Gene

IDBG-636002 (NPHS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017022	myosin binding

Biological Process

GO:0000165	MAPK cascade
GO:0007155	cell adhesion
GO:0007254	JNK cascade
GO:0007519	skeletal muscle tissue development
GO:0007520	myoblast fusion
GO:0030838	positive regulation of actin filament polymerization
GO:0032836	glomerular basement membrane development
GO:0044062	regulation of excretion
GO:0072015	glomerular visceral epithelial cell development

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0036057	slit diaphragm
GO:0042995	cell projection
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF00041
PF01108
PF07679
PF07686
PF08205

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite