InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NEFH

Summary

InnateDB Protein

IDBP-688055.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEFH

Protein Name

neurofilament, heavy polypeptide

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000029508

InnateDB Gene

IDBG-636145 (NEFH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005198	structural molecule activity
GO:0019901	protein kinase binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0006334	nucleosome assembly
GO:0033693	neurofilament bundle assembly
GO:0045104	intermediate filament cytoskeleton organization
GO:0045110	intermediate filament bundle assembly
GO:0048936	peripheral nervous system neuron axonogenesis
GO:0060052	neurofilament cytoskeleton organization
GO:0061564	axon development
GO:1902513	regulation of organelle transport along microtubule

Cellular Component

GO:0000786	nucleosome
GO:0005739	mitochondrion
GO:0005882	intermediate filament
GO:0005883	neurofilament
GO:0030424	axon
GO:0097418	neurofibrillary tangle

Protein Structure and Domains

PDB ID

InterPro

IPR001664 Intermediate filament protein
IPR005819 Histone H5
IPR010790 Protein of unknown function DUF1388

PFAM

PF00038
PF07142

PRINTS

PR00624

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MSQ6

UniProt Splice Variant

Entrez Gene

528842

UniGene

RefSeq

XP_002694652

HUGO

HGNC:7737

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02045602

GenPept