Version 5.4
Bos taurus Protein: BT.87427
Summary
InnateDB Protein IDBP-688121.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.87427
Protein Name E3 ubiquitin-protein ligase NRDP1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000038019
InnateDB Gene IDBG-636215 (BT.87427)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005128 erythropoietin receptor binding
GO:0005135 interleukin-3 receptor binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016881 acid-amino acid ligase activity
GO:0031386 protein tag
GO:0046872 metal ion binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0008285 negative regulation of cell proliferation
GO:0010468 regulation of gene expression
GO:0016567 protein ubiquitination
GO:0030336 negative regulation of cell migration
GO:0043408 regulation of MAPK cascade
GO:0045619 regulation of lymphocyte differentiation
GO:0045637 regulation of myeloid cell differentiation
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051865 protein autoubiquitination
GO:0051896 regulation of protein kinase B signaling
GO:0097191 extrinsic apoptotic signaling pathway
GO:2000114 regulation of establishment of cell polarity
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR003613 U box domain
IPR008974 TRAF-like
IPR015036 USP8 interacting
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF04564
PF08941
PF00097
PRINTS
PIRSF
SMART SM00184
SM00504
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N658
UniProt Splice Variant
Entrez Gene 614134
UniGene
RefSeq NP_001039990
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013531 DAAA02013532 DAAA02013533
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca