Version 5.4
| Bos taurus Protein: SF3A1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-688275.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SF3A1 | ||||||||
| Protein Name | Splicing factor 3A subunit 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000004398 | ||||||||
| InnateDB Gene | IDBG-636352 (SF3A1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 118 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000061
SWAP/Surp IPR000626 Ubiquitin-like IPR022030 Pre-mRNA splicing factor PRP21-like protein IPR029071 Ubiquitin-related domain |
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| PFAM |
PF01805
PF00240 PF14560 PF12230 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00648
SM00213 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A2VDN6 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 504381 | ||||||||
| UniGene | Bt.7260 | ||||||||
| RefSeq | NP_001074979 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC133328 | ||||||||
| GenPept | AAI33329 | ||||||||