Version 5.4
Bos taurus Protein: CACYBP
Summary
InnateDB Protein IDBP-688287.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACYBP
Protein Name Calcyclin-binding protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000001464
InnateDB Gene IDBG-636368 (CACYBP)
Protein Structure
UniProt Annotation
Function May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1) (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005641 nuclear envelope lumen
GO:0005737 cytoplasm
GO:0030877 beta-catenin destruction complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007052 CS domain
IPR007699 SGS
IPR008978 HSP20-like chaperone
IPR015120 Siah interacting protein, N-terminal
PFAM PF04969
PF05002
PF09032
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3T168
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 618428
UniGene Bt.20607
RefSeq NP_001029981
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102091
GenPept AAI02092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca