Version 5.4
Bos taurus Protein: GDF11
Summary
InnateDB Protein IDBP-688398.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDF11
Protein Name growth differentiation factor 11
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009755
InnateDB Gene IDBG-636472 (GDF11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008083 growth factor activity
Biological Process
GO:0001501 skeletal system development
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0008285 negative regulation of cell proliferation
GO:0009887 organ morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0021512 spinal cord anterior/posterior patterning
GO:0031016 pancreas development
GO:0040007 growth
GO:0045596 negative regulation of cell differentiation
GO:0048469 cell maturation
GO:0048593 camera-type eye morphogenesis
GO:0060021 palate development
Cellular Component
GO:0005615 extracellular space
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR001111 Transforming growth factor-beta, N-terminal
IPR001839 Transforming growth factor-beta, C-terminal
IPR029034 Cystine-knot cytokine
PFAM PF00688
PF00019
PRINTS
PIRSF
SMART SM00204
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 540517
UniGene
RefSeq XP_001788528
HUGO HGNC:4216
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca