InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GPN1

Summary

InnateDB Protein

IDBP-688420.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPN1

Protein Name

GPN-loop GTPase 1

Synonyms

XAB1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005098

InnateDB Gene

IDBG-636492 (GPN1)

Protein Structure

UniProt Annotation

Function

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0017111	nucleoside-triphosphatase activity

Biological Process

GO:0008152

metabolic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR003593 AAA+ ATPase domain
IPR004130 Uncharacterised protein family, ATP binding
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF03029

PRINTS

PR00315

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A4FUD1

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

508522

UniGene

Bt.13501

RefSeq

NP_001076861

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC114712

GenPept

AAI14713