InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.62162

Summary

InnateDB Protein

IDBP-688697.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.62162

Protein Name

tyrosine-protein kinase ABL2

Synonyms

ABLL;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020006

InnateDB Gene

IDBG-636736 (BT.62162)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0030145	manganese ion binding

Biological Process

GO:0006468	protein phosphorylation
GO:0007015	actin filament organization
GO:0010976	positive regulation of neuron projection development
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0051017	actin filament bundle assembly
GO:0051353	positive regulation of oxidoreductase activity
GO:0071300	cellular response to retinoic acid

Cellular Component

GO:0015629

actin cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003646 SH3-like domain, bacterial-type
IPR011511 Variant SH3 domain
IPR015015 F-actin binding
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM