InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC25A3

Summary

InnateDB Protein

IDBP-688743.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC25A3

Protein Name

Phosphate carrier protein, mitochondrial

Synonyms

D1S155E;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017131

InnateDB Gene

IDBG-636777 (SLC25A3)

Protein Structure

UniProt Annotation

Function

Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).

Subcellular Localization

Mitochondrion inner membrane {ECO:0000269PubMed:2036364}; Multi-pass membrane protein {ECO:0000269PubMed:2036364}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.

Predicted by orthology
Total	63 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015293	symporter activity
GO:0032403	protein complex binding

Biological Process

GO:0006810	transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain

PFAM

PF00153

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P12234

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

282477

UniGene

Bt.4880

RefSeq

NP_777082

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC149996 X05340 X77338

GenPept

AAI49997 CAA28951