Version 5.4
Bos taurus Protein: ZNF326
Summary
InnateDB Protein IDBP-688754.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF326
Protein Name zinc finger protein 326
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025469
InnateDB Gene IDBG-636761 (ZNF326)
Protein Structure
UniProt Annotation
Function Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000993 RNA polymerase II core binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0032784 regulation of DNA-templated transcription, elongation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016363 nuclear matrix
GO:0044609 DBIRD complex
Protein Structure and Domains
PDB ID
InterPro IPR007071 A-kinase anchoring protein 95 (AKAP95)
PFAM PF04988
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt F1MJM0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 533643
UniGene Bt.37485
RefSeq NP_001192957
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120193 DAAA02007944
GenPept AAI20194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca