Version 5.4
Bos taurus Protein: GRIN2A
Summary
InnateDB Protein IDBP-688773.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRIN2A
Protein Name glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010376
InnateDB Gene IDBG-636790 (GRIN2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity
GO:0005215 transporter activity
GO:0005216 ion channel activity
GO:0005234 extracellular-glutamate-gated ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
Biological Process
GO:0001964 startle response
GO:0001975 response to amphetamine
GO:0006810 transport
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0007268 synaptic transmission
GO:0007611 learning or memory
GO:0007612 learning
GO:0007613 memory
GO:0008104 protein localization
GO:0008542 visual learning
GO:0009611 response to wounding
GO:0019233 sensory perception of pain
GO:0022008 neurogenesis
GO:0030431 sleep
GO:0033058 directional locomotion
GO:0034220 ion transmembrane transport
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035249 synaptic transmission, glutamatergic
GO:0040011 locomotion
GO:0042177 negative regulation of protein catabolic process
GO:0042391 regulation of membrane potential
GO:0042417 dopamine metabolic process
GO:0042428 serotonin metabolic process
GO:0042493 response to drug
GO:0043065 positive regulation of apoptotic process
GO:0045471 response to ethanol
GO:0048167 regulation of synaptic plasticity
GO:0050804 regulation of synaptic transmission
GO:0051930 regulation of sensory perception of pain
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 regulation of excitatory postsynaptic membrane potential
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0009986 cell surface
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 cell junction
GO:0030425 dendrite
GO:0042734 presynaptic membrane
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0097481 neuronal postsynaptic density
Protein Structure and Domains
PDB ID
InterPro IPR001320 Ionotropic glutamate receptor
IPR001508 NMDA receptor
IPR001638 Extracellular solute-binding protein, family 3
IPR018884 Glutamate [NMDA] receptor, epsilon subunit, C-terminal
IPR019594 Glutamate receptor, L-glutamate/glycine-binding
PFAM PF00060
PF00497
PF10565
PF10613
PRINTS PR00177
PIRSF
SMART SM00079
SM00062
SM00918
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F2Y8F0
UniProt Splice Variant
Entrez Gene
UniGene Bt.88638
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057431 HQ826801
GenPept ADZ53754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca