Version 5.4
Bos taurus Protein: LITAF
Summary
InnateDB Protein IDBP-688963.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LITAF
Protein Name lipopolysaccharide-induced TNF factor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007391
InnateDB Gene IDBG-636988 (LITAF)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0050699 WW domain binding
Biological Process
GO:0001817 regulation of cytokine production
GO:0007165 signal transduction
GO:0032496 response to lipopolysaccharide
GO:0042347 negative regulation of NF-kappaB import into nucleus
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR006629 LPS-induced tumor necrosis factor alpha factor
PFAM PF10601
PRINTS
PIRSF
SMART SM00714
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2KHV3
UniProt Splice Variant
Entrez Gene 520564
UniGene Bt.88639
RefSeq NP_001039717
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112870 DAAA02057483 GJ062847
GenPept AAI12871 DAA15592

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca