InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DUSP22

Summary

InnateDB Protein

IDBP-688990.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DUSP22

Protein Name

dual specificity phosphatase 22

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000039071

InnateDB Gene

IDBG-637000 (DUSP22)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006470	protein dephosphorylation
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0016311	dephosphorylation
GO:0042127	regulation of cell proliferation
GO:0046330	positive regulation of JNK cascade

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR020417 Atypical dual specificity phosphatase
IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00782

PRINTS

PR00700
PR01908

PIRSF

SMART

SM00194
SM00195

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt