Version 5.4
Bos taurus Protein: PEX16
Summary
InnateDB Protein IDBP-689023.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PEX16
Protein Name Peroxisomal membrane protein PEX16
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004065
InnateDB Gene IDBG-637034 (PEX16)
Protein Structure
UniProt Annotation
Function Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3 (By similarity). {ECO:0000250}.
Subcellular Localization Peroxisome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0006625 protein targeting to peroxisome
GO:0007031 peroxisome organization
GO:0016557 peroxisome membrane biogenesis
GO:0016558 protein import into peroxisome matrix
GO:0022615 protein to membrane docking
GO:0032581 ER-dependent peroxisome organization
GO:0045046 protein import into peroxisome membrane
GO:0070972 protein localization to endoplasmic reticulum
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR013919 Peroxisome membrane protein, Pex16
PFAM PF08610
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KII7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510447
UniGene
RefSeq XP_005216504
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03090303 BC112623
GenPept AAI12624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca