InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HARBI1

Summary

InnateDB Protein

IDBP-689221.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HARBI1

Protein Name

Putative nuclease HARBI1

Synonyms

C11orf77; C15H11orf77;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006085

InnateDB Gene

IDBG-637222 (HARBI1)

Protein Structure

UniProt Annotation

Function

Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity (By similarity). {ECO:0000250, ECO:0000305}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Interaction with NAIF1 promotes translocation to the nucleus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Detected in brain. {ECO:0000269PubMed:15169610}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004518	nuclease activity
GO:0016787	hydrolase activity
GO:0016788	hydrolase activity, acting on ester bonds
GO:0046872	metal ion binding

Biological Process

GO:0008152	metabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome

Protein Structure and Domains

PDB ID

InterPro

IPR006912 Harbinger transposase-derived protein, plant

PFAM

PF04827

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q17QR8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

514442

UniGene

Bt.37438

RefSeq

NP_001069136

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC118217

GenPept

AAI18218