Version 5.4
Bos taurus Protein: ARHGAP1
Summary
InnateDB Protein IDBP-689236.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP1
Protein Name Rho GTPase activating protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000041467
InnateDB Gene IDBG-637238 (ARHGAP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0030675 Rac GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0032321 positive regulation of Rho GTPase activity
GO:0032855 positive regulation of Rac GTPase activity
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0001726 ruffle
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0031252 cell leading edge
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR001251 CRAL-TRIO domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PF00650
PF13716
PRINTS
PIRSF
SMART SM00324
SM00516
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6RWK1
UniProt Splice Variant
Entrez Gene 512817
UniGene Bt.15773
RefSeq NP_001179991
HUGO HGNC:673
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041585
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca