InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MAP2K4

Summary

InnateDB Protein

IDBP-689256.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAP2K4

Protein Name

dual specificity mitogen-activated protein kinase kinase 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041598

InnateDB Gene

IDBG-637253 (MAP2K4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.

Predicted by orthology
Total	46 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000165	MAPK cascade
GO:0006468	protein phosphorylation
GO:0071260	cellular response to mechanical stimulus

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A5PJP8

UniProt Splice Variant

Entrez Gene

526469

UniGene

Bt.23717

RefSeq

NP_001092508

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC142195 DAAA02048884 DAAA02048885 DAAA02048886

GenPept

AAI42196